I have changed telescopes more often than my wardrobe. My primary interest has always been imaging and I have used a variety of instruments, each with their own strengths and limitations. I have owned the following instruments over the past decade:
Celestron: C8 and C11
Meade: SN-8 and SN-10
Takahashi: FS-60, FS-102, FS-128, Mewlon 210,
Mewlon 250
Vixen: R200SS, NA140SS
Astro-Tech 8-RC
My current optical tubes are an Orion 10 in. f/4.7 Newtonian, Orion 120ED refractor, and Pentax 75 EDHF refractor. The 10 in. is a nice fast scope, and the largest tube that I can fit on my mount. The 120ED (900mm FL) is a nice sized, well-corrected scope for mid-sized objects. I exchanged the stock focuser with a Moonlite one. I now use this and the Pentax 75 EDHF primarily as my field scopes.
My mount is an older Losmandy G11 that was reworked and fitted with Gemini. I have changed my guidescope setup and am now using a Lumicon 50mm Super Finder as a "guidescope." I guide with an Orion StarShoot Autoguider (SSAG) on the permanent mount and a Celestron NexGuide stand-alone guider for my field mount.
My fielf mount is an Orion Sirius EQ-G. I utilize an improvised side-by-side mounting plate that can accomodate the guidescope as well as imaging scope (or a variety of telephoto lenses). This unit is comprised of a Losmandy universal dovetail plate and two dovetail plate adapters. Flexure is not a problem with this setup.
I use a variety of 35mm lenses for imaging:
Canon 300/4
Nikon 180/2.8 (pictured below)
Takumar 24/3.5, 28/3.5, 35/3.5, 55/1.8, 135/3.5 and 200/4
My digital SLRs are a Canon 1000D (Digital Rebel XS) camera that was modified by Hutech and a 550D (Rebel T2i) modified by Hap Griffin. When shooting with these cameras, I use live view function to focus my image. For post-processing, I use ImagesPlus to calibrate, align and combine images and RegiStar to align images from different scopes. I always use Photoshop to make final adjustments.